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Menopause International

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Menopause Int 2009;15:169-174
doi:10.1258/mi.2009.009041
© 2009 British Menopause Society

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Reviews

Endometriosis: associations with menopause, hormone replacement therapy and cancer

Manisha Palep-Singh  and Sujata Gupta

Department of Gynaecology, Saint Mary's University Hospital, CMMC NHS Trust, Manchester, UK

Correspondence: Manisha Palep-Singh MD MRCOG, Consultant Gynaecologist and Subspecialist in Reproductive Medicine and Surgery, Department of Gynaecology, Saint Mary's University Hospital, CMMC NHS Trust, Hathersage Road, Manchester M13 0JH, UK. Email: Manisha.Palep-Singh{at}cmft.nhs.uk
Endometriosis is an estrogen-dependent condition and is characterized by the presence of ectopic endometrial tissue. The pathogenesis of this condition remains an enigma. Endometriosis has well known associations with menopause both in terms of secondary outcomes from medical and surgical therapy in premenopausal women, as well as a natural occurrence/recurrence of the disease in women going through menopause naturally. This review article aims to discuss the current day modalities of management of endometriosis with their pros and cons especially in the context of menopause and cancer.

Key Words: Endometriosis • menopause • hormone replacement therapy • cancer


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