Menopause International > Volume 14, Number 2 > Pp. 85-87

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Clinical practice

Epilepsy in older women

Nitin K Sethi and Cynthia L Harden 

Comprehensive Epilepsy Center, Weill Cornell Medical College, NY, USA

Correspondence: Cynthia L Harden MD, Professor of Neurology, Comprehensive Epilepsy Center, Weill Cornell Medical College, 525 East 68th Street, Room K-615, New York, NY 10021, USA. Email: clharden{at}med.cornell.edu
Women suffering from epilepsy require special attention throughout their life. In this review, management of epilepsy during the periods of perimenopause, menopause and late maturity is discussed. The effect of epilepsy on age at menopause, changes in seizure frequency during perimenopause and menopause, and the risks of hormone replacement therapy are also presented. Altered antiepileptic drug pharmacokinetics with increasing age and the management of this vulnerable population is also discussed.

Key Words: Epilepsy • hormone replacement therapy • menopause • perimenopause • pharmacokinetics

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