Menopause International > Volume 14, Number 2 > Pp. 83-84

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Short report

Use of unopposed systemic estrogen therapy in non-hysterectomized women: a population-based study in the UK

Margaret Rees ^*  and Sally Hope 

^* Women's Centre, John Radcliffe Hospital, Oxford
Woodstock Surgery, Oxford, UK

Correspondence: Margaret Rees. Reader in Reproductive Medicine, University of Oxford, Visiting Professor, University of Glasgow, Honorary Consultant in Medical Gynaecology, Level 4, Women's Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK. Email: margaret.rees{at}obs-gyn.ox.ac.uk
A population study of 28 general practices in Oxfordshire, UK found that 0.028% of 17,712 non-hysterectomized women aged 45–60 years were using systemic unopposed estrogen. This is significantly lower than that reported in the Million Women Study.

Key Words: Endometrial cancer • estrogen • Million Women Study • progestogen • unopposed estrogen

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